Evaluation of Platelet Function After Statin Loading Dose in Patients Before Percutaneous Coronary Intervention
Status:
Completed
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of a loading dose of two different
statins on platelet reactivity (atorvastatin, metabolized by CYP3A4, and rosuvastatin, which
is rather independent of this enzyme)in patients at least 5 days in therapy with aspirin and
clopidogrel (with or without an undergoing treatment with statins) undergoing PCI for
coronary disease with chronic stable angina and/or evidence of inducible myocardial ischemia.