Evaluation of Predictors of Aortic Aneurysm Growth and Rupture

• Status: Active, not recruiting
• Trial end date: 2022-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal is to non-invasively study the metabolic processes within the aortic wall that are thought to explain progression to clinical manifestations of an aortic aneurysm.

Hypothesis is that the non-invasive imaging of Abdominal Aortic Aneurysm (AAA) with contrast ultrasound, coupled with serum biomarker measurements will allow the identification of the vulnerable aortic wall and patients who are at risk of AAA growth or rupture.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rabih A. Chaer; University of Pittsburgh
• Collaborator: National Institute on Aging (NIA)

Criteria

Inclusion Criteria:

• Diagnosis of AAA with confirmation of diagnosis of any size aneurysm with imaging.

• 21 years of age or older

• ability to give informed consent.

Exclusion Criteria:

• Inability to provide an informed consent

• Known allergy to Definity

• Unstable cardiopulmonary conditions

• pregnancy