Evaluation of Reduced-volume PEG Bowel Preparation Administered the Same Day of Colonoscopy

• Status: Completed
• Trial end date: 2010-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The conventional total dose of 4 L of polyethylene glycol (PEG) given the day before the procedure is safe and effective. It has been the standard cleansing regimen for the last 25 years. To overcome the difficulty in completing the bowel preparation due to large volume and/or taste, reduced-volume (mixed) bowel preparation of bisacodyl and 2 L of PEG have been shown to provide adequate colon cleansing and better tolerability.

LoVol-esse is a reduced-volume PEG-based bowel preparation to be used in combination with bisacodyl and designed to improve patient tolerability and attitude toward bowel cleansing prior to colonoscopy thanks to the reduced volume and improved taste. The present study is intended to compare the new dosing regimen of the bowel lavage solution given the same day compared with standard PEG formulation (SELG 1000) given the day before colonoscopy.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Catholic University of the Sacred Heart
• Treatments: Bisacodyl

Criteria

Inclusion Criteria:

• both sexes

• aged between 18 and 85 yr

• undergoing a complete colonoscopy

Exclusion Criteria:

• known or suspected gastrointestinal obstruction or perforation

• toxic megacolon

• major colonic resection

• pregnant or at risk of becoming pregnant women

• lactating women

• inability to comprehend the full nature and purpose of the study

• no signed informed consent prior to inclusion in the study

• known or suspected hypersensitivity to the active principles or other ingredients

• history of anaphylaxis to drugs or allergic reactions in general