Evaluation of Tamsulosin in the Treatment of Ureteral Stones

• Status: Completed
• Trial end date: 2006-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Ureteral stones have an important place in daily urological practice, usually causing acute episodes of ureteral colic by obstructing the urinary tract. The aim of the study is to evaluate whether repeated administration of tamsulosin, a drug routinely used in the treatment of lower urinary tract symptoms, could lower the delay of elimination of the stone in patients with pelvis ureterolithiasis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rennes University Hospital
• Collaborators: Ministry of Health, France; Yamanouchi
• Treatments: Tamsulosin

Criteria

Inclusion Criteria:

• Adult over 18 years

• Emergency admission for a ureteral colic

• Radio-opaque ureterolithiasis

• Stone of 2 to 7 mm diameter

• Informed written consent

Exclusion Criteria:

• Pregnancy or breast-feeding

• Treatment with alpha or beta-blocker

• Contraindication to tamsulosin (orthostatic hypertension, hepatic failure)

• Complication needing surgery

• Calculi spontaneous passage before randomization

• Patient not available for a 6 week follow-up