Evaluation of Three Continuation Therapies After ECT Concerning Efficacy and Cognition in Severly Depressed Patients

• Status: Completed
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate three different continuation treatments after acute ECT concerning efficacy and impact on cognition in severly depressed patients.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Charite University, Berlin, Germany
• Collaborator: German Research Foundation
• Treatments: Antidepressive Agents; Lithium Carbonate

Criteria

Inclusion Criteria:

• Major depressive episode (unipolar)

• Response to acute ECT (at least 50% reduction in HAMD)

• Capacity to consent

• Sufficient comprehension of the German language

Exclusion Criteria:

• Schizophrenia, schizoaffective disorder, or other psychosis

• Amnestic disorder, dementia, or delirium

• Pregnancy

• Epilepsy

• Current alcohol or substance abuse or dependence

• CNS disease or brain injury not associated with psychotropic drug exposure

• ECT in the past 3 months

• Acute suicidality

• Judiciary hospitalization