Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
Status:
Completed
Trial end date:
2008-04-01
Target enrollment:
Participant gender:
Summary
There is some controversy in the medical literature regarding the effectiveness of topical
lidocaine in children as an adjuvant drug to upper gastrointestinal endoscopy. In children,
deep sedation and general anesthesia are often used to sedate children submitting to this
procedure. Propofol is an anesthetic drug increasingly popular in this situation, but this
drug can only be used with an anesthesiologist in Brazil. Its main side effects include
hypotension, respiratory depression and local pain. Lidocaine is frequently used as
premedication, and the rationale is that lowering patient discomfort could lower the required
dose to achieve the endoscopy and reduce potential side effects. Nevertheless, some patients
perceive this medication as uncomfortable. This study aims to compare sedative drug doses
between patients who were given either placebo or topical lidocaine.