Overview

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

Status:
Active, not recruiting
Trial end date:
2027-02-01
Target enrollment:
Participant gender:
Summary
This is a randomized, two-arm, open-label Phase II multicenter study designed to examine the effects of adding bevacizumab to ixabepilone for the treatment of patients who have recurrent or persistent platinum-resistant/refractory epithelial (non-mucinous) ovarian, fallopian tube, or primary peritoneal cancer. Its primary objective is to assess whether adding bevacizumab to ixabepilone improves progression-free survival in its target population. Study participants will be stratified by (a) study site and (b) previous receipt of bevacizumab prior to randomization.
Phase:
Phase 2
Details
Lead Sponsor:
Yale University
Collaborators:
R-Pharm US, Inc.
R-Pharm-US, LLC
Treatments:
Bevacizumab
Epothilones