Evaluation of a Synthetic Bone Substitute for Ridge Preservation

• Status: Completed
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Fifteen patients were selected, each presenting at least two jaw front teeth indicated for extraction: in the Test Group (TG), post-extraction sockets was filled by synthetic bone substitute ReproBone, and in the Control Group (CG) the socket was filled only by clot. In both groups, the sockets were covered by a resorbable collagen membrane BioMend, which in turn was covered by a flap. Computed tomography scans were acquired in the immediate postoperative period and 6 months after surgery, and the horizontal and vertical dimensional changes in bone crests were quantified.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Sao Paulo

Criteria

Inclusion Criteria:

• At least 20 teeth

• Minimum of two upper front teeth with indication for extraction after clinical and radiographic examinations.

Exclusion Criteria:

• Subjects were excluded if they had systemic involvement that can interfere with periodontal treatment (e.g.: osteoporosis, diabetes, hypertension decompensated heart disease)

• Prolonged use of anti-inflammatory or steroids

• Known allergy to any biomaterial used in the study

• Smokers

• Or who were pregnant/lactating or developed this systemic condition throughout the study.