Evaluation of the Analgesic Effect of Dexmedetomidine Versus Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries

• Status: Completed
• Trial end date: 2018-05-06
• Target enrollment: 0
• Participant gender: Male

Summary

To determine if the epidural route provide an acceptable analgesia in spine surgeries and avoided the need for excessive IV analgesics. Also to determine whatever dexmedetomidine or fentanyl is more better neuroaxial adjuvant regarding providing early onset and prolonged analgesia and stable cardiorespiratory parameters

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Collaborators: ismaiel saied hammad; Mohamed Mahmoud Mohamed; Mohamed, Ahmed A., M.D.; Tarek Ahmed Radwan
• Treatments: Analgesics; Bupivacaine; Dexmedetomidine; Fentanyl

Criteria

Inclusion Criteria:

1. All male patients between the age group of 18 and 65 years

2. Patients of American Society of Anaesthesiologists (ASA) class I and II.

3. Patients who will undergo lumbar spine surgeries (laminectomy ± discectomy for PIVD (Prolapse of intervertebral disc), will be enrolled for this study

Exclusion Criteria:

1. All Patients below the age of 18 years and above 65 years. Also All female patient are excluded from the study.

2. Other spine surgeries rather than laminectomy, also surgeries on more than two levels.

3. Patients with haematological disease, bleeding or coagulation test abnormalities, psychiatric diseases.

4 .Patiensts with history of drug abuse, allergy to any study medication. . 4 .Patients with cervical and thoracic spine surgeries, tubercular spine , any permanent neurological disorders and vertebral deformeties such as scoliosis and spondylolisthesis.

5. Pregnant and lactating patients .

Withdrawal criteria :

Accidental Dural puncture.