Evaluation of the Clinical Practice of Using of a 70% Ethanol Lock Solution for the Prevention of Catheter Related Blood Stream Infections in Pediatric Patients Undergoing Intestinal Rehabilitation

• Status: Withdrawn
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the clinical practice of the prophylactic use of ethanol locks for the prevention of catheter related blood stream infections in pediatric intestinal rehabilitation program patients requiring total parenteral nutrition.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Nebraska
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• Signed informed consent/assent and willingness to adhere to protocol

• Intestinal rehabilitation patients with documented short bowel syndrome

• Age: newborn to 19 years of age

• Indwelling tunneled venous catheter placed for the purpose of total parenteral nutrition/IV fluids, with a 2 hour or longer window out of 24 hours for ethanol lock instillation

• No history of alcohol abuse

• No history of hypersensitivity to ethanol

• No history or documented active seizure disorder

Exclusion Criteria:

• Parent/guardian unwilling to sign consent

• Active bacterial infection

• Non-tunneled, non-permanent catheter (triple lumen or PICC)

• Pre-existing condition that would prevent enrollment as determined by each patients' physician

• Inability to adhere to protocol