Overview

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
0
Participant gender:
All
Summary
Study evaluates the drug-drug interaction between Ticagrelor and Venlafaxine when taken together in healthy volunteers
Phase:
Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
AstraZeneca
Treatments:
Ticagrelor
Venlafaxine Hydrochloride
Criteria
Inclusion Criteria:

- a weight of at least 50 kg and a body mass index between 18 to 30 kg/m2

Exclusion Criteria:

- History of clinically significant disease or disorder as judged by the investigator

- Any clinically significant illness, medical/surgical procedure or trauma within 4
weeks of the first administration of drug.

- History of haemophilia, von Willebrand´s disease, lupus anticoagulant or other
diseases/syndromes that may alter or increase bleeding.

- History of previous or ongoing psychiatric disease