Evaluation of the Effect of 3HP vs Periodic 3HP vs 6H in HIV-Positive Individuals
Status:
Completed
Trial end date:
2019-10-18
Target enrollment:
Participant gender:
Summary
This study is a parallel, two part, open label, individually randomized, pragmatic trial
among HIV-positive individuals. Part A compares a single round of weekly high dose
rifapentine plus isoniazid for three months (3HP) to six months of daily isoniazid (6H). Part
B compares periodic 3HP (p3HP) to a single round of 3HP.
Phase:
Phase 3
Details
Lead Sponsor:
KNCV Tuberculosis Foundation The Aurum Institute NPC
Collaborators:
Aurum Institute Johns Hopkins University London School of Hygiene and Tropical Medicine