Evaluation of the Effectiveness of Photodynamic Therapy in the Treatment of Lesions of the Lichen Planus Type in the Oral Mucosa and Its Diagnostics With the Use of Autofluorescence, in Various Wavelength Ranges, in Combination With the Use of Textu

• Status: Completed
• Trial end date: 2021-06-10
• Target enrollment: 0
• Participant gender: All

Summary

Lesions of the lichen planus type within the oral mucosa are now considered a potentially cancerous condition. One of the minimally invasive methods of treating these lesions is photodynamic therapy, and the gold standard in therapy is topical steroid administration

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wroclaw Medical University
• Treatments: Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• histological diagnosis of OLP

• non smoker

• no diabetes melitus

• no hepatitis

Exclusion Criteria:

• diabetes melitus

• hepatitis

• occurrence dysplasia in the histopathological specimen;

• use of lichenoid reaction inducing medication and presence of amalgam fillings nearby the lesions;

• interventions for OLP in the previous 12 weeks;

• pregnant or breastfeeding women;

• proved or suspected hypersensitivity to any of the chemicals used in the treatment