Overview Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype Status: Terminated Trial end date: 2020-11-14 Target enrollment: Participant gender: Summary This study will evaluate the efficacy, safety and pharmacokinetics (PK) of VX-814 in PiZZ subjects. Phase: Phase 2 Details Lead Sponsor: Vertex Pharmaceuticals Incorporated