Overview Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype Status: Completed Trial end date: 2021-05-04 Target enrollment: Participant gender: Summary This study will evaluate the efficacy, safety and pharmacokinetics (PK) of VX-864 in PiZZ subjects. Phase: Phase 2 Details Lead Sponsor: Vertex Pharmaceuticals Incorporated