Evaluation of the Efficacy of Acitretin Therapy for Nail Psoriasis
Status:
Completed
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
Objective:
Efficacy of systemic retinoid therapy of nail psoriasis has never been assessed objectively.
Evaluate therapeutic efficacy of acitretin in patients with isolated nail psoriasis.
Design:
Open-study on thirty-six patients with moderate to severe nail psoriasis treated with
acitretin.
Participants:
Patients included 27 men and 9 women (mean age 41) with nail psoriasis. Intervention: Therapy
consisted of acitretin 0.2 to 0.3 mg/Kg/day for 6 months.
Main Outcome Measure(s):
Clinical evaluation, NAPSI and modified NAPSI scores before therapy, every 2 months during
therapy and 6 months after treatment.