Evaluation of the Efficacy of Pirfenidone in Progressive Chronic Hypersensitivity Pneumonitis
Status:
Completed
Trial end date:
2020-06-30
Target enrollment:
Participant gender:
Summary
This study aims to evaluate the efficacy of pirfenidone in chronic hypersensitivity
pneumonitis. This study included 40 adult patients (≥ 18 years) with a diagnosis of chronic
progressive hypersensitivity pneumonitis. The included patients were divided into 2 groups 20
patients in each one.
Group 1: will receive pirfenidone in addition to the conventional treatment Group 2: will be
maintained on conventional treatment. Forced vital capacity (FVC),6 minutes walking
test(6MWT), oxygen tension in the arterial blood (PaO2), and St. George's Respiratory
Questionnaire (SGRQ ) were measured before and after 6 months of a pirfenidone treatment
trial.
Results