Evaluation of the Mixture Myoinositol:D-chiro-inositol 3.6:1 in Women With Polycystic Ovary Syndrome

• Status: Completed
• Trial end date: 2017-05-05
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of the present study is to evaluate the effect of increasing the proportion of D-chiro-inositol (DCI) in a combination with myo-inositol (MYO) in improving fertility in women with polycystic ovarian syndrome (PCOS). Sixty women diagnosed with PCOS will randomly take twice a day for 12 weeks a capsule containing 550 mg of myo-inositol and 150 mg of D-chiro-inositol or capsules containing 550 mg of myo-inositol and 13.8 mg of D-chiro-inositol.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Biosearch S.A.
• Treatments: Inositol

Criteria

Inclusion Criteria:

• Being diagnosed with PCOS according to Rotterdam criteria.

• Being in in vitro fertilization treatment.

• Body mass index less than 30 kg/m2.

• Accept freely to participate in the study and sign the informed consent document.

Exclusion Criteria:

• Contraindication to perform techniques of assisted reproduction or stimulation of ovulation.

• Advanced state of endometriosis (III or IV).

• Classified as poor responder in fertility treatment.

• Premature ovarian failure.

• Severe male factor (cryptozoospermia).

• Few expectations of compliance and/or collaboration.