Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients
Status:
Terminated
Trial end date:
2005-07-01
Target enrollment:
Participant gender:
Summary
The aim of this randomized study is to compare the occurrence of lipoatrophy in HIV-1
infected, naive patients receiving either a nucleoside reverse transcriptase inhibitor
(NRTI)-sparing antiretroviral therapy with non-nucleoside reverse transcriptase inhibitor
(NNRTI) and boosted protease inhibitor (PI), or a standard antiretroviral therapy with 2 NRTI
plus either PI or NNRTI. Lipoatrophy is evaluated by measurement of fat volume by computed
tomography (CT)-scan and DEXA (Dual Energy X-ray Absorptiometry).
Phase:
Phase 4
Details
Lead Sponsor:
French National Agency for Research on AIDS and Viral Hepatitis
Treatments:
HIV Protease Inhibitors Protease Inhibitors Reverse Transcriptase Inhibitors