Evaluation of the Potentiating Effect of tDCS on Opioid Analgesia of Pain Threshold in Humans

• Status: Unknown status
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to evaluate the potential additive effect of tDCS compared to placebo-sham in opioid analgesia on pain thresholds in nociceptive experimental model in healthy volunteers .

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hospital de Clinicas de Porto Alegre
• Treatments: Analgesics, Opioid; Remifentanil

Criteria

Inclusion Criteria:

• Male

• Healthy

• Without medication

• Sign the informed consent

Exclusion Criteria:

• Patients who did not understand the Portuguese

• Acute or chronic pain conditions

• Medical or psychiatric disorders

• History of sleep disorders (apnea, hypersomnia, somnambulism…)

• History of alcohol or substance abuse

• Neurological disorder

• Use of anti-inflammatory drugs, steroids and non-steroids, opioid and non-opioid analgesics, psychiatric medications, anticonvulsants, alpha and beta blockers

• Traumatic brain injury

• Neurosurgery

• Metallic implant in the brain