Overview

Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors

Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
Patients with recurrent or refractory solid tumors or brain tumors that are unresponsive to conventional therapy, or with no known effective therapy, will be treated. Experiments in the laboratory have shown the experimental drug RAD001C (RAD001, Everolimus) can prevent cells from multiplying. RAD001 is now being tested in diseases such as cancer, in which excessive cell multiplication needs to be stopped. The drug has been tested in adult cancer patients and has been well tolerated by subjects in these studies. It is experimental and, therefore, available in clinical trials.
Phase:
Phase 1
Details
Lead Sponsor:
St. Jude Children's Research Hospital
Collaborator:
Novartis
Treatments:
Everolimus
Sirolimus