Overview

Examination of the Bronchoprotective Effect of Endothelin Receptor Blockade in Asthma

Status:
Unknown status
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study will be to determine if blockade of endothelin 1 signalling via endothelin receptor A using ambrisentan or dual blockade (A&B) via bosentan can provide protection against methacholine induced bronchoconstriction in asthma.
Phase:
Phase 2
Details
Lead Sponsor:
University of Glasgow
Collaborator:
NHS Greater Glasgow and Clyde
Treatments:
Ambrisentan
Bosentan