Exchange Transfusion Versus Plasma From Convalescent Patients With Methylene Blue in Patients With COVID-19

• Status: Recruiting
• Trial end date: 2020-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this project is to introduce way for treatment of patients with severe COVID-19 disease with respiratory complications.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Methylene Blue

Criteria

Inclusion Criteria:

1. Adult patients are 18 years old or above.

2. Inpatients diagnosed as severe COVID - 19 disease according to WHO criteria.

3. CT chest with extensive lung disease (ground-glass and consolidative pulmonary opacities).

4. O2 saturation less than 93% resting.

5. Respiratory rate equal or more than 30 per minute.

Exclusion Criteria:

1. Patients with pregnancy and lactation.

2. Renal failure and heart failure.

3. Contraindication for plasma or blood transfusion.