Overview

ExclUsive endocRine Therapy Or Partial Breast Irradiation for Women Aged ≥70 Years Early Stage Breast Cancer

Status:
Recruiting
Trial end date:
2030-01-15
Target enrollment:
Participant gender:
Summary
Rationale and relevance for patients and the scientific community. In low risk early stage patients ≥70 years, exclusive Partial Breast Irradiation (PBI) as radiation therapy (RT) approach might be superior in terms of Health-Related Quality of Life (HRQoL), when compared to exclusive endocrine therapy (ET) following breast-conserving surgery (BCS). Assuming an equal rate of disease control, unnecessary long-term toxicity of ET may be avoided.
Phase:
Phase 3
Details
Lead Sponsor:
Azienda Ospedaliero-Universitaria Careggi
Collaborators:
Institut Curie
University of Florence
Treatments:
Anastrozole
Exemestane
Letrozole
Phenobarbital
Tamoxifen