Exercise and Acarbose in Type 2 Diabetes

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the impact of exercise training, Acarbose, and the combination of exercise and Acarbose on glycemic control, body composition, insulin sensitivity and other cardiovascular risk markers in type 2 diabetes. Further, muscle biopsies will be obtain to study gene expression. Our hypothesis is that the combination therapy will be superior to monotherapy with exercise or Acarbose.

• Phase: Phase 4

Details

• Lead Sponsor: Karolinska Institutet
• Collaborators: Bayer; The Swedish Medical Research Council; The Swedish Research Council
• Treatments: Acarbose

Criteria

Inclusion Criteria: Men and women, diagnosis of type 2 diabetes established since at least three months, treatment with diet or maximum one oral anti-diabetic drug, GHb < 8.5 %, age 45 - 60 years, BMI 25 - 30 kg/m2, no participation in any regular exercise program.

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Exclusion Criteria: Unable to perform exercise, significant GI-disease, severe heart-disease, renal failure

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