Exogenous Melatonin in Intensive Care Unit Chronodisruption
Status:
Unknown status
Trial end date:
2019-11-15
Target enrollment:
Participant gender:
Summary
To this day, a small number of studies have evaluated the effect of melatonin on the
modifications of the characteristics of sleep in critical care units, with mostly a small
studied population. However, no study has been realized on a large population, nor has it
evaluated the association between genetic factors and response to treatment (melatonin),
hence the originality of our study. In our study we hypothesized that systematic melatonin
usage in ICU can ameliorate the total sleep time and the fragmentation index and can decrease
the confusion related to sleep deprivation.