Exparel for Postoperative Pain Management in Shoulder Surgery

• Status: Completed
• Trial end date: 2017-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the effect of liposomal Bupivacaine infiltration into the shoulder to continues nerve block with Bupivacaine on postoperative pain control and functional outcomes.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wayne State University
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Patients undergoing shoulder arthroplasty under general anesthesia

• Patients undergoing open reduction internal fixation (ORIF) of a proximal humerus fracture under general anesthesia

• Patients with American Society of Anesthesiologist (ASA) physical status classification of 1-3

• Patients meeting criteria for standard of care continuous peripheral nerve block (CPNB) per anesthesia guidelines.

• Patients agreeing to be available for brief follow up telephone survey post- operatively and being mentally able to respond.

• Patients available for follow up routine post-operative clinic visits, per standard of care.

Exclusion Criteria:

• Contraindications to regional anesthesia

• Significant peripheral neuropathy or neurological disorder affecting the upper extremity

• Contraindication to a component of multimodal analgesia

• Pregnancy

• Opioid tolerance

• Cognitive or psychiatric condition that might affect patient assessment and/or inability to provide informed consent.