Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD
Status:
Completed
Trial end date:
2015-08-03
Target enrollment:
Participant gender:
Summary
This study measures biological and psychological processes that might help researchers to
better understand what is taking place during low or medium dose and full dose MDMA-assisted
psychotherapy treatment in people with PTSD. Heart rate variability (HRV) will be measured up
to three times; before and once or twice after receiving MDMA-assisted psychotherapy. Brain
activity will be measured before and after MDMA-assisted psychotherapy in response to
personalized trauma-related scripts. Participants will complete a measure of self-compassion
at baseline and two months after a final experimental treatment session. Therapy techniques
observed during recorded treatment sessions will be classified using a standardized clinical
measure.
Details
Lead Sponsor:
Multidisciplinary Association for Psychedelic Studies