Aims :
- exploring lorazepam (0.038 mg/kg) effects, after a single oral intake, in healthy
volunteers, on the neural correlates of encoding and retrieval of information during a
word-stem completion task (implicit memory), using fMRI
- comparing lorazepam effects to diazepam (0.3 mg/kg)effects
- exploring benzodiazepines effects, after a single oral intake, on the neural correlates
of successful encoding of information within explicit memory using fMRI
Hypothesis :
- both diazepam and lorazepam will impair explicit memory performance, but lorazepam only
will impair perceptual priming
- lorazepam and diazepam will modify the normal correlates of information encoding within
explicit memory
- lorazepam only will alter the neural correlates of perceptual priming