Extended Letrozole Regimen Co-treatment With Gonadotropin Releasing Hormone Antagonist Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in Poor Responders Undergoing IVF-ET

• Status: Recruiting
• Trial end date: 2020-04-20
• Target enrollment: 0
• Participant gender: Female

Summary

The object of this study is to evaluate the efficacy of extended letrozole co-treatment with GnRH-antagonist protocol in ovarian stimulation of poor responder patients undergoing IVF-ET.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Cetrorelix; Estradiol; Estradiol 17 beta-cypionate; Estradiol 3-benzoate; Hormone Antagonists; Hormones; Letrozole; LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)-; Polyestradiol phosphate; Prolactin Release-Inhibiting Factors

Criteria

Inclusion Criteria:

• Poor responders according to the ESHRE Bologna criteria

Exclusion Criteria:

Age > 42 years FSH> 12 IU/L Irregular menstrual cycles Unilateral ovary Polycystic ovary syndrome Endometriosis Male factor of infertility requiring ICSI History of recurrent miscarriage Endocrinologic disorders Systemic disease contraindicating pregnancy