Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry
Status:
Completed
Trial end date:
2020-12-24
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the effectiveness of extended-release naltrexone
(XR-NTX) vs. enhanced treatment-as-usual (TAU) among opioid dependent adults leaving NYC
jails. In parallel, we propose to recruit a matched, quasi-experimental methadone cohort,
which will result in a naturalistic comparison of XR-NTX vs. an established jail-based
methadone treatment program standard-of-care. Our primary aim is to compare time-to-relapse
among participants treated with XR-NTX vs. randomized TAU controls and time-to-relapse among
XR-NTX arm vs. jail-based MTP participants, following release from jail. Secondary aims will
compare related opioid treatment outcomes post-release across all arms.
Phase:
Phase 4
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health
Collaborators:
Friends Research Institute, Inc. National Institute on Drug Abuse (NIDA) University of California, Los Angeles