Overview

Extended-release Pharmacotherapy for Opioid Use Disorder

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The primary objective is a clinical superiority effectiveness contrast to standard of care. Reported following SPIRIT and CONSORT standards, the study will determine whether extended-release injectable depot Buprenorphine (XR-Bup) maintenance therapy for OUD over six months is clinically superior to standard-of-care, oral medication (sublingual Buprenorphine [SL-Bup] or oral methadone [Met]; together: Bup/Met)
Phase:
Phase 3
Details
Lead Sponsor:
King's College London
Collaborators:
Bangor University
Birmingham and Solihull Mental Health NHS Foundation Trust
Cumbria, Northumberland Tyne and Wear NHS Foundation Trust
Greater Manchester Mental Health NHS Foundation Trust
NHS Tayside
South London and Maudsley NHS Foundation Trust
Treatments:
Buprenorphine
Methadone