Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD)
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
Chronic graft-versus-host disease (cGVHD) is a long-lasting complication that can occur after
transplants. The transplanted cells seem to fight with the patient's own cells.
Extracorporeal photopheresis (ECP) is a fairly new procedure for cGVHD. The participant gets
a port to hook up to a machine. The machine removes the white blood cells, mixes them with a
light-sensitive drug, shines light on it, and puts all the blood back in.
This study will find out if patients respond better if they get ECP with methoxsalen, in
addition to the pills normally used to treat cGVHD.