Overview

Ezetimibe in Patients Hypo-responsive to Statins

Status:
Terminated
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
Response to statin therapy for elevated low density lipoprotein is variable and may be influenced by cholesterol absorption. This study will evaluate whether combination therapy with atorvastatin/ezetimibe will be superior to atorvastatin alone in subjects who have less than 25% LDL reduction on starting dose statin (eg, atorvastatin 10 mg daily or simvastatin 20 mg daily).
Phase:
Phase 3
Details
Lead Sponsor:
University of California, San Diego
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Atorvastatin
Atorvastatin Calcium
Ezetimibe