F 18 T807 Tau PET Imaging of Progressive Posterior Cortical Dysfunction (IND 123119, Protocol E)
Status:
Completed
Trial end date:
2020-10-20
Target enrollment:
Participant gender:
Summary
This project will collect quantitative pilot data that will allow the characterization of
uptake and binding of 18F-AV-1451 (also known as F 18 T807), a novel tau imaging compound, in
individuals with Progressive Posterior Cortical Dysfunction (PPCD) and logopenic variant
primary progressive aphasia (lvPPA). The primary goal is to develop tau imaging technique as
an antecedent biomarker of cognitive decline. The investigators propose to obtain preliminary
data that will support the possibility of detecting cognitive decline in its earliest stages,
before the occurrence of dementia.
Details
Lead Sponsor:
Tammie L. S. Benzinger, MD, PhD Washington University School of Medicine