FFA-Induced Hypertension and Endothelial Dysfunction
Status:
Completed
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
The study is a prospective open label study to examine the effects of oral and intravenous
fat load on blood pressure, endothelial function, sympathetic activity, and oxidative stress
in obese healthy subjects. Subjects will receive either 8-hour of intravenous or oral fat
loads in either low or high doses or normal saline in random order. Blood samples are drawn
and vitals are measured before and after the infusions. Endothelial function and plasma
glucose and lipid levels are measured to study the effects.