Our primary hypothesis is that [18F]FLT PET can identify active bone marrow in addition to
metabolically active tumor.
This trial will use FLT-PET imaging to define areas of active bone marrow in the pelvis. The
radiation plan is then designed to spare that area, in hopes of keeping the bone marrow
active during therapy. Bone marrow and tumor activity will be monitored using a sequence of
FLT PET scans during the course of chemotherapy and radiation therapy.