FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial
Status:
Recruiting
Trial end date:
2024-08-31
Target enrollment:
Participant gender:
Summary
This study aims :
- To assess the efficacy of fluorometholone 0.1% one drop twice daily for four weeks in
reducing the incidence of post-operative trachomatous trichiasis (TT) when given as
adjunctive therapy with TT surgery in the programmatic setting
- To assess whether such treatment is sufficiently safe for wide-scale implementation in
TT programs.
- To estimate the costs of adding fluorometholone 0.1% treatment to TT surgery per case of
postoperative TT averted, and to characterize the value of such treatment under a range
of plausible health economic circumstances
Phase:
Phase 3
Details
Lead Sponsor:
Massachusetts Eye and Ear Infirmary
Collaborators:
Berhan Public Health and Eye Care Consultancy Berhan Public Health and Eye Care Consultancy PLC Fred Hollows Foundation London School of Hygiene and Tropical Medicine The Fred Hollows Foundation, Australia The Fred Hollows Foundation, Ethiopia University of Pennsylvania