Overview FRAGRANCE Part A Safety: Study to Find a Genetic Signature of de Novo Resistance to Letrozole Status: Completed Trial end date: 2014-12-01 Target enrollment: Participant gender: Summary Find a genetic signature of de novo resistance to letrozole in adjuvant breast cancer; Phase: Phase 2 Details Lead Sponsor: Jules Bordet InstituteCollaborators: Feculdade de Medicina da Universidade de Sao Paulo - BrasilHospital de Clinicas de Porto AlegreHospital do Cancer, Sao PauloTreatments: Letrozole