Fabry: Renal Function During Long-term ERT by 51Cr-EDTA Clearance

• Status: Completed
• Trial end date: 2016-12-09
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study was to investigate renal function decline by measured glomerular filtration rate (mGFR) in patients with FD during enzyme replacement therapy, and to explore the influence of age on renal function in FD.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ulla Feldt-Rasmussen

Criteria

Inclusion Criteria:

• Genetically and/or enzymatically verified Fabry disease

Exclusion Criteria:

• End-stage renal disease prior to baseline (GFR <15 ml/min/1.73m2, dialysis or renal transplant)

• Patient has not received enzyme replacement therapy during follow-up

• Patient has had less than 3 measurement of GFR during follow-up