Fast-Release Orodispersible Tramadol Tablet (Tradonal Odis®) as Analgesia for Hysterosalpingography
Status:
Completed
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
This study evaluates the analgetic effects of the fast-release orodispersible tramadol
tablet.
Tramadol acts through a weak affinity for μ receptors and secondly by inhibiting
noradrenaline and serotonin neuronal reuptake. It has been used since the 1970s by over 50
million people for the treatment of acute and chronic pain. The orodispersible Tramadol
tablet is a new galenic form and is available on the Belgian market for the last three years.
Pregastric absorption leads to a quicker onset of action.
So far, evidence shows that pain during and immediately after the Hysterosalpingography (HSG)
procedure is only significantly reduced by IV opioid analgesia. This study evaluates the
analgetic potential of an orodispersible opioid tablet. This tablet disintegrates rapidly (in
around 20-30 seconds) and may be taken without water. Its abuse potential is very low and its
respiratory depressant effect is negligible.