Overview

Feasibility of Assessing Lymphoma Response to Precise Local Injection of Candidate Chemotherapy Agents

Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
Many cancer patients are prescribed drugs to which their cancer is already resistant - and thus suffer toxicity with no potential for benefit. Previous attempts to assess chemoresistance or sensitivity in vitro have failed. This is a feasibility study in human patients with newly diagnosed or recurrent lymphoma to determine how human cancerous lymph nodes in situ respond to standard of care therapeutics precisely microinjected with the CIVO(tm) microdosing system.
Phase:
Phase 1
Details
Lead Sponsor:
Presage Biosciences
Collaborators:
Fred Hutchinson Cancer Research Center
National Cancer Institute (NCI)
National Institutes of Health (NIH)
Treatments:
Bendamustine Hydrochloride
Doxorubicin
Liposomal doxorubicin
Methylprednisolone
Methylprednisolone acetate
Methylprednisolone Hemisuccinate
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate
Rituximab
Vincristine