Feasibility of the Utilization of Buprenorphine in the Emergency Room to Treat Clinical Opioid Withdrawal

• Status: Completed
• Trial end date: 2018-08-28
• Target enrollment: 0
• Participant gender: All

Summary

The investigators are trying to determine whether they can effectively treat patients suffering from acute opioid withdrawal in the Emergency Department at Virginia Commonwealth University Health System (VCUHS) and subsequently transfer them to an outpatient addiction clinic within the existing infrastructure. This will be a descriptive investigation of the process to reveal areas of success and opportunities for improvement in order to determine feasibility of the study procedures in preparation for a larger clinical investigation.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Virginia Commonwealth University
• Treatments: Analgesics, Opioid; Buprenorphine

Criteria

Inclusion Criteria:

• Opioid overdose only, of any formulation or route, with complete reversal of toxicity after naloxone by any route.

• RR ≥ 12

• Pulse oximetry > 95%

• GCS 15

• Clinical Opioid Withdrawal Scale (COWS) score ≥ 8

Exclusion Criteria:

• Pregnancy

• Prisoner

• Incomplete reversal of toxicity related to metrics above

• Police custody

• Known allergy to buprenorphine

• Emergent psychiatric condition including active suicidality that requires admission

• Emergent medical condition that requires admission