Fentanyl Use for Sedation in Esophagogastroduodenoscopy

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether conscious sedation with a narcotic and sedative (in combination) is as efficacious as a sedative alone for elective upper endoscopy to achieve optimal patient comfort and ease of procedure.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: St. Joseph's Healthcare Hamilton
• Collaborator: McMaster University
• Treatments: Fentanyl; Midazolam

Criteria

Inclusion Criteria:

• outpatient elective upper endoscopy

• age 18-65

• able to give consent

Exclusion Criteria:

• mental incompetency

• pregnancy

• weight <55kg or 110 lbs

• emergent procedures,

• known hypersensitivity or allergy to fentanyl or midazolam

• chronic use of benzodiazepines or opioids

• patients known a priori to require therapeutic interventions in conjunction with their EGD

• patients to have major cardiorespiratory comorbidities, obstructive sleep apnea, liver cirrhosis, or renal failure