Fentanyl and Propofol for Tracheal Intubation During Sevoflurane Induction Without Muscle Relaxants in Children

• Status: Completed
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Several methods have been proposed to improve intubating conditions and minimize sevoflurane induction time during sevoflurane induction in children. These include clonidine premedication, [5] addition of nitrous oxide, [6] opioids, [7,8] or propofol [9].

Four Studies evaluated sevoflurane alone for intubation (9-12).Aim of this study: is to evaluate the effects of two different dose of propofol preceded by a fixed dose of fentanyl during sevoflurane induction on quality of tracheal intubation in children undergoing elective surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: King Saud University
• Treatments: Fentanyl; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• ASA physical status I and II patients, Undergoing elective ENT surgery

Exclusion Criteria:

• • History or examination suggested a potentially difficult intubation,

• Significant respiratory disease or poorly controlled asthma,

• gastrooesophageal reflux,

• neurological or neuromuscular disease,

• any condition that would preclude the use of this technique,

• known sensitivity to the drugs used,

• history or examination suggestive of cardiac illness,

• history of respiratory tract infection in the previous 2 weeks,

• history of malignant hyperthermia or other myopathy,

• who refused to undergo an inhalational induction,

• Children in whom i.v. access had already been established.