Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia

• Status: Unknown status
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to compare the effects of ciprofibrate versus omega-3 fatty acid supplementation on the vascular structure and function in hypertensive patients with hypertriglyceridemia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Universitario Pedro Ernesto
• Collaborator: Rio de Janeiro State Research Supporting Foundation (FAPERJ)
• Treatments: Ciprofibrate

Criteria

Inclusion Criteria:

• Previous diagnosis of hypertension

• Patients with serum triglycerides levels ≥ 150 mg/dl and <500 mg/dl

• Patients on stable antihypertensive medication for at least 4 weeks

• Patients with food consumption maintained for at least 4 weeks

Exclusion Criteria:

• Smoking

• Secondary hypertension

• Hormone replacement therapy

• Diabetes mellitus

• Chronic kidney disease

• Known coronary artery disease

• Previous stroke

• Dyslipidemia severe, with LDL cholesterol> 160 mg/dL or triglycerides ≥ 500 mg/dl

• Use of statins or beta blockers