Floxuridine, Dexamethasone, and Irinotecan After Surgery in Treating Patients With Liver Metastases From Colorectal Cancer
Status:
Completed
Trial end date:
2004-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as floxuridine, dexamethasone, and irinotecan,
use different ways to stop tumor cells from dividing so they stop growing or die. Hepatic
arterial infusion uses a catheter to deliver chemotherapy directly to the liver. Combining
more than one drug and giving them in different ways may kill any tumor cells remaining after
surgery.
PURPOSE: Phase II trial to study the effectiveness of irinotecan combined with hepatic
arterial infusion with floxuridine and dexamethasone after surgery in treating patients who
have liver metastases from colorectal cancer.