Fludarabine and Intermediate-dose TBI Followed by PTCy in Patients Undergoing Allo Transplant for Heme Malignancies

• Status: NOT_YET_RECRUITING
• Trial end date: 2031-10-15

Summary

The Flu-TBI 800 trial is a prospective, single-arm, multicenter, interventional phase 2 study to evaluate whether fludarabine plus intermediate-dose total body irradiation (TBI 800 cGy) with post-transplant cyclophosphamide (PTCy) (experimental regimen) improves the 1-year survival of allogeneic stem cell transplant recipients.

• Phase: PHASE2

Details

• Lead Sponsor: Hackensack Meridian Health
• Treatments: Cyclophosphamide; fludarabine; fludarabine phosphate; Mycophenolic Acid; Tacrolimus