Fludarabine and Thalidomide in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as fludarabine, work in different ways to stop
cancer cells from dividing so they stop growing or die. Biological therapies such as
thalidomide use different ways to stimulate the immune system and stop cancer cells from
growing. Combining fludarabine with thalidomide may kill more cancer cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of thalidomide when
given together with fludarabine and to see how well they work in treating patients with newly
diagnosed B-cell chronic lymphocytic leukemia.