Flurbiprofen Axetil for Uterine Contraction Pain

• Status: Completed
• Trial end date: 2008-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

Uterine contraction pain is a common problem after abortion. Optimal analgesic for such suffering is still needed to be guaranteed. Flurbiprofen Axetil is a target-distributable non-steroidal anti-inflammatory drug (NSAID) functioning via block the synthesis of prostaglandin E (PGE). The investigators hypothesized that Flurbiprofen Axetil could suppress the uterine contraction pain after abortion effectively.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nanjing Medical University
• Treatments: Flurbiprofen; Flurbiprofen axetil; Propofol

Criteria

Inclusion Criteria:

• ASA status I-II

• Performing abortion operation (medical- or drug-induced

• Requiring painless abortion

Exclusion Criteria:

• < 19yrs, and >= 45yrs

• History of central active drugs administration

• Drug abuse

• Hypertension

• Diabetes

• Any other chronic diseases

• Allergy to the study drugs

• Habit of over-volume alcohol drinking

• Records of history of centrally active drug use and psychiatry

• Any organic disorders